A Short Synthesis Concerning Biological Effects and Equivalent Doses in Radiotherapy

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Submitted: March 31, 2017
Published: Feb 15, 2017
DOI: 10.29328/journal.jro.1001005
Keywords:
Radiobiology, Fractionation, Equivalent, Dose, Time effect, Linear quadratic, Repopulation
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Cyril Voyant
University of Corsica, CNRS UMR SPE 6134, (Campus Grimaldi, 20250 Corte), France
Daniel Julian
CGS cancérologie du grand Montpellier, 34000 Montpellier, France

Abstract

The limits of classical equivalent computation based on time, dose, and fractionation (TDF) and linear quadratic models have been known for a long time. Medical physicists and physicians are required to provide fast and reliable interpretations regarding the delivered doses or any future prescriptions relating to treatment changes. In this letter, we propose an outline related to the different models usable for equivalent and biological doses that are likely to be the most appropriate. The used methodology is based on: the linear-quadratic-linear model of Astrahan, the repopulation effects of Dale, and the prediction of multi-fractionated treatments of Thames.

Article Details

Voyant, C., & Julian, D. (2017). A Short Synthesis Concerning Biological Effects and Equivalent Doses in Radiotherapy. Journal of Radiology and Oncology, 1(1), 039–045. https://doi.org/10.29328/journal.jro.1001005
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Copyright (c) 2017 Voyant C, et al.

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