Photon Absorption characteristics of some selected Enzyme Inhibitors used in Cancer Research in the Energy range 1 keV-100 GeV

Main Article Content

Mustafa Recep Kaçal
Hüseyin Ali Karataş
Ferdi Akman

Abstract

The absorption parameters such as total mass attenuation coefficients, molecular, atomic, and electronic cross sections, effective atomic numbers and electron densities were calculated for some selected enzyme inhibitors in the photon energy range from 1 keV up to 100 GeV. The changes in the absorption parameters were interpreted with the photoelectric effect, Compton scattering and pair production processes. It is observed that the 2-Imino-1-imidazolidineacetic acid enzyme inhibitor has more radiation shielding feature when compared to other chosen enzyme inhibitors. The present investigation is anticipated to be useful for researchers studying with radiation in several fields and cancer researchers.

Article Details

Kaçal, M. R., Ali Karataş, H., & Akman, F. (2017). Photon Absorption characteristics of some selected Enzyme Inhibitors used in Cancer Research in the Energy range 1 keV-100 GeV. Journal of Radiology and Oncology, 1(2), 060–068. https://doi.org/10.29328/journal.jro.1001009
Case Reports

Copyright (c) 2017 Kaçal MR, et al.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Mustafa Recep Kaçal

Giresun University, Sciences and Arts Faculty, Department of Physics, 28100 Giresun, Turkey

Florey K. Analytical profiles of drug substances. Volume 15. Academic Press. 1986.

Umezawa H. Antibiotics (Corcoran JW, Hahn FE Eds.). Springer-Verlag. 1975; 3.

Padayatty SJ, Marcelli M, Shao TC, Cunningham GR. Lovastatin-induced apoptosis in prostate stromal cells. J Clin Endocrinol Metab. 1997; 82: 1434-1439. Ref.: https://goo.gl/PWNE2M

Sayyed MI, Issa SAM, Auda SH. Assesment of radio-protective properties of some antiflammatory drugs. Prog Nucl Energ. 2017; 100: 297-308. Ref.: https://goo.gl/ofyNiw

More CV, Bhosale RR, Pawar PP. Detection of new polymer materials as gamma-ray-shielding materials. Radiat Eff Def Solids. 2017; 172: 469-484. Ref.: https://goo.gl/8MUS1q

Gaikwad DK, Pawar PP, Selvam TP. Mass ateenuation coefficients and effective atomic numbers of biological compounds for gamma ray interactions. Radiat Phys Chem. 2017; 138: 75-80. Ref.: https://goo.gl/uzksLC

Isikli Z, Oto B. Gamma or X-rays attenuation properties of some biochemical compounds. Radiat Eff Def Solids. 2017; 172: 296-304. Ref.: https://goo.gl/iorniU

Akman F, Kacal MR, Akman F, Soylu MS. Determination of effective atomic numbers and electron densities from mass attenuation coefficients for some selected complexes containing lanthanides. Can J Phys. 2017. Ref.: https://goo.gl/2oKQDC

Akman F, Kacal MR, Akdemir F, Araz A, Turhan MF, et al. Calculation of absorption parameters for selected narcotic drugs in the energy range from 1 keV to 100 GeV. AIP Conference Proceedings. 2017. Ref.: https://goo.gl/xHQVji

Kumar A. Studies on effective atomic number and electron densities of nucleobases in DNA. Radiat Phys Chem. 2016; 127: 48-55. Ref.: https://goo.gl/oZh2yY

Akman F, Akman F, Kacal MR, Turhan MF, Akdemir F, et al. Investigation of chemical effect on the absorption parameters for some selected indium complex at 59.54 keV photon energy. Journal of Physics: Conference Series. 2016; 707. Ref.: https://goo.gl/WYBFXH

Akman F, Durak R, Kacal MR, Bezgin F. Study of absorption parameters around the K edge for selected compounds of Gd. X-ray Spectrom. 2016; 45: 103-110. Ref.: https://goo.gl/w8gjKc

Akman F, Durak R, Turhan MF, Kacal MR. Studies on effective atomic numbers, electron densities from mass attenuation coefficients near the K edge in some samarium compounds. Appl Radiat Isotopes. 2015; 101: 107-113. Ref.: https://goo.gl/9xasyJ

Kore PS, Pawar PP. Measurements of mass attenuation coefficient, effective atomic number and electron density of some amino acids. Radiat Phys Chem. 2014; 98: 86-91. Ref.: https://goo.gl/En8MFw

Manjunatha HC. A study of photon interaction in some hormones. Radiat Eff Def Solids. 2013; 168: 385-398. Ref.: https://goo.gl/ekuiQb

Manjunatha HC, Rudraswamy B. Study of effective atomic number and electron density for tissues from human organs in the energy range of 1 keV-100 GeV. Health Phys. 2013; 104: 158-162. Ref.: https://goo.gl/pgs8bx

Kacal MR, Han I, Akman F. Measurement of mass attenuation coefficients by Si(Li), NaI(Tl), and Cd(Tl) detectors. Nuclear Science and Technology. 2012: 59-69. Ref.: https://goo.gl/MVn9sc

Manjunatha HC. Influence of gamma irradiation on conductivity of YBa2Cu3O7. Radiat Phys Chem. 2015; 113: 24-27. Ref.: https://goo.gl/C7YJEs

Seenappa L, Manjunatha HC, Chandrika BM, Chikka H. A study of shielding properties of X-ray and gamma in barium compounds. J Radiat Protec Researc. 2017; 42: 26-32. Ref.: https://goo.gl/aYVwuW

Manjunatha HC. A study of gamma attenuation parameters in poly methyl methacrylate and Kapton. Radiat Phys Chem. 2017; 137: 254-259. Ref.: https://goo.gl/hWj4Np

Gerward L, Guilbert N, Jensen KB, Levring H. X-ray absorption in matter, reengineering XCOM. Radiat Phys Chem. 2001; 60: 23-24. Ref.: https://goo.gl/kLDMU1