Abstract

Case Report

A Short Synthesis Concerning Biological Effects and Equivalent Doses in Radiotherapy

Cyril Voyant*, Cyril Voyant* and Daniel Julian

Published: 15 April, 2017 | Volume 1 - Issue 1 | Pages: 039-045

The limits of classical equivalent computation based on time, dose, and fractionation (TDF) and linear quadratic models have been known for a long time. Medical physicists and physicians are required to provide fast and reliable interpretations regarding the delivered doses or any future prescriptions relating to treatment changes. In this letter, we propose an outline related to the different models usable for equivalent and biological doses that are likely to be the most appropriate. The used methodology is based on: the linear-quadratic-linear model of Astrahan, the repopulation effects of Dale, and the prediction of multi-fractionated treatments of Thames.

Read Full Article HTML DOI: 10.29328/journal.jsmt.1001036 Cite this Article Read Full Article PDF

Keywords:

Radiobiology; Fractionation; Equivalent; Dose; Time effect; Linear quadratic; Repopulation

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