Abstract

Case Report

Incidental findings in traditional nuclear medicine practice

Giuseppe De Vincentis, Mariano Pontico, Maria Ricci, Viviana Frantellizzi* and Mauro Liberatore

Published: 28 July, 2018 | Volume 2 - Issue 2 | Pages: 036-040

The presence of an incidental finding, defined as an abnormality which is unrelated to the initial scanning indication, is widely increases due to the access to new devices and imaging modalities. This growing number of incidental findings can lead to additional medical care including unnecessary tests nevertheless, in a minority of patients, can lead to diagnosis of an important and unexpected condition that could be crucial for the patient. We reported three cases in which nuclear medicine imaging, performed for different reasons and showed a relevant and unexpected pathology. In the case 1, a bone scan, performed in a 66 aged woman for breast cancer staging, allowed the diagnosis of a uterine fibroma. In the case 2, a HMPAO labeled-WBC scintigraphy performed because of a suspect of osteomyelitis, showed a remarkable heart-shaped photopenic area, highly suggestive of cardiac global dilatation. In the case 3, a 62 aged man referred to bone scintigraphy for the staging of recent diagnosed lung cancer. The bone scan allowed the diagnosis of a meningioma. Therefore, the occurrence of incidental findings could lead to reveal relevant abnormalities for the diagnostic pathway.  

Read Full Article HTML DOI: 10.29328/journal.jro.1001019 Cite this Article Read Full Article PDF

Keywords:

Nuclear Medicine; Incidental findings; Risk conditions

References

  1. Lumbreras B, Donat L, Hernández-Aguado I. Incidental findings in imaging diagnostic tests: a systematic review. Br J Radiol. 2010; 83: 276-289. Ref.: https://tinyurl.com/ya6huxpr
  2. Priola AM, Priola SM, Giaj-Levra M, Basso E, Veltri A, et al. Clinical implications and added costs of incidental findings in an early detection study of lung cancer by using low-dose spiral computed tomography. Clin Lung Cancer. 2013; 14: 139-148. Ref.: https://tinyurl.com/y8254vq7
  3. Coward J, Lawson R, Kane T, Elias M, Howes A, et al. Multi-centre analysis of incidental findings on low-resolution CT attenuation correction images. Br J Radiol. 2014; 87: 20130701. Ref.: https://tinyurl.com/ycoe9t4n
  4. Lumbreras B, Gonz´alez-AlvarezI, G ´omez-S´aez N, Fermina Lorente M, Hern´andez-Aguado I. Management of patients with incidental findings in imaging tests: a large prospective single-center study. Clin Imaging. 2014; 38: 249-254. Ref.: https://tinyurl.com/ybsqp9tj
  5. de Vries EF, Roca M, Jamar F, Israel O, Signore A. Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine. Eur J Nucl Med Mol Imaging. 2010; 37: 842-848. Ref.: https://tinyurl.com/y82gszvc
  6. Bunnik EM, van Bodegom L, Pinxten W, de Beaufort ID, Vernooij MW. Ethical framework for the detection, management and communication of incidental findings in imaging studies, building on an interview study of researchers' practices and perspectives. BMC Med Ethics. 2017; 18: 10. Ref.: https://tinyurl.com/yanbhy2j
  7. Treskes K, Bos SA, Beenen LFM, Sierink JC, Edwards MJR, et al. High rates of clinically relevant incidental findings by total-body CT scanning in trauma patients; results of the REACT-2 trial. Eur Radiol. 2017; 27: 2451-2462. Ref.: https://tinyurl.com/ycdt7nhe
  8. Priola AM, Priola SM, Giaj-Levra M, Basso E, Veltri A, et al. Clinical Implications and Added Costs of Incidental Findings in an Early Detection Study of Lung Cancer by Using Low-Dose Spiral Computed Tomography. Clin Lung Cancer. 2013; 14: 139-148. Ref.: https://tinyurl.com/y8254vq7

Figures:

Figure 1

Figure 1

Figure 1

Figure 2

Figure 1

Figure 3

Figure 1

Figure 4

Similar Articles

  • Clinically and Radiological isolated syndrome (MS risk)
    Hassan Ahmed Hashem*, Yasser Hamed Mustafa, Abdelazim M Reda, Sameh Azab and Ahmed M Solaiman Hassan Ahmed Hashem*,Yasser Hamed Mustafa,Abdelazim M Reda,Sameh Azab,Ahmed M Solaiman. Clinically and Radiological isolated syndrome (MS risk). . 2018 doi: 10.29328/journal.jro.1001020; 2: 041-046
  • Incidental findings in traditional nuclear medicine practice
    Giuseppe De Vincentis, Mariano Pontico, Maria Ricci, Viviana Frantellizzi* and Mauro Liberatore Giuseppe De Vincentis,Mariano Pontico,Maria Ricci,Viviana Frantellizzi*,Mauro Liberatore. Incidental findings in traditional nuclear medicine practice. . 2018 doi: 10.29328/journal.jro.1001019; 2: 036-040
  • Ra-223 dichloride management in a Nuclear Medicine Unit: experience of a referral institution
    Giulia Anna Follacchio*, Viviana Frantellizzi, Francesco Monteleone, Giuseppe De Vincentis and Mauro Liberatore Giulia Anna Follacchio*,Viviana Frantellizzi,Francesco Monteleone,Giuseppe De Vincentis,Mauro Liberatore. Ra-223 dichloride management in a Nuclear Medicine Unit: experience of a referral institution. . 2017 doi: 10.29328/journal.jro.1001010; 1: 069-078

Recently Viewed

Read More

Most Viewed

Read More